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Sami S Zoghbi Selected Research

Breast Neoplasms (Breast Cancer)

12/2022First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.
9/2016(18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier.
6/201311C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains.
6/2010N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier.

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Sami S Zoghbi Research Topics

Disease

20Neuroinflammatory Diseases
04/2023 - 02/2008
14Inflammation (Inflammations)
01/2022 - 08/2007
10Alzheimer Disease (Alzheimer's Disease)
01/2020 - 04/2004
4Breast Neoplasms (Breast Cancer)
12/2022 - 06/2010
3Schizophrenia (Dementia Praecox)
01/2019 - 11/2012
3Substance-Related Disorders (Drug Abuse)
10/2018 - 03/2012
3Major Depressive Disorder (Major Depressive Disorders)
01/2014 - 10/2012
3Parkinson Disease (Parkinson's Disease)
04/2007 - 01/2002
2Neoplasms (Cancer)
01/2022 - 10/2021
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018 - 01/2001
1Colorectal Neoplasms (Colorectal Cancer)
01/2022
1Ovarian Neoplasms (Ovarian Cancer)
10/2021
1Polyostotic Fibrous Dysplasia (McCune Albright Syndrome)
11/2020
1Rheumatoid Arthritis
05/2020
1Migraine Disorders (Migraine)
01/2019
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
01/2019
1Tauopathies
01/2019
1Alcoholism (Alcohol Abuse)
11/2018
1Mental Disorders (Mental Disorder)
11/2018
1Atrophy
01/2017
1Epilepsy (Aura)
12/2015
1Drug Resistant Epilepsy
08/2015
1Temporal Lobe Epilepsy
08/2015
1Cognitive Dysfunction
07/2013
1Edema (Dropsy)
01/2013
1Multiple Sclerosis
09/2011
1Porphyrias (Porphyria)
08/2010
1Brain Ischemia (Cerebral Ischemia)
01/2007
1Brain Diseases (Brain Disorder)
07/2005
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
07/2004
1Tinnitus
01/2004
1Tobacco Use Disorder (Nicotine Dependence)
01/2001

Drug/Important Bio-Agent (IBA)

24Proteins (Proteins, Gene)FDA Link
12/2022 - 07/2009
20Biomarkers (Surrogate Marker)IBA
01/2022 - 08/2007
8GABA-A Receptors (GABA(A) Receptor)IBA
07/2009 - 01/2004
4EnzymesIBA
05/2020 - 10/2012
4LigandsIBA
01/2013 - 01/2006
3Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
11/2020 - 07/2005
3pyridineIBA
01/2006 - 01/2001
2Glycoproteins (Glycoprotein)IBA
12/2022 - 06/2013
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2022 - 05/2020
2Adenosine Monophosphate (AMP)IBA
11/2020 - 07/2005
22- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA
01/2019 - 01/2008
2CannabinoidsIBA
11/2018 - 11/2012
2Dopamine (Intropin)FDA LinkGeneric
10/2018 - 04/2007
2multidrug resistance-associated protein 1IBA
09/2016 - 06/2010
2RolipramIBA
01/2014 - 11/2012
2Amyloid beta-PeptidesIBA
01/2008 - 04/2004
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2006 - 01/2001
1Fluorine-18IBA
04/2023
1Macrophage Colony-Stimulating FactorIBA
04/2023
1Celecoxib (Celebrex)FDA Link
01/2022
1Cyclooxygenase 1IBA
10/2021
1Ketoprofen (Orudis)FDA LinkGeneric
10/2021
111C-PS13IBA
10/2021
1GTP-Binding Proteins (G-Protein)IBA
11/2020
1ProstaglandinsIBA
05/2020
1LipopolysaccharidesIBA
05/2020
1O-GlcNAc transferaseIBA
01/2020
1hexosaminidase CIBA
01/2019
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
01/2019
15-HT1B Serotonin ReceptorIBA
01/2019
1SmokeIBA
11/2018
1Phospholipases (Phospholipase)IBA
01/2018
1Staphylococcal Protein A (Protein A)IBA
11/2016
1N-Methylaspartate (NMDA)IBA
12/2015
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2015
1CarbonIBA
08/2015
1Serotonin (5 Hydroxytryptamine)IBA
12/2014
1Amyloid (Amyloid Fibrils)IBA
07/2013
1S 10 (S-10)IBA
07/2013
1metabotropic glutamate receptor type 1IBA
06/2013
1AntigensIBA
01/2013
1Phosphodiesterase 4 InhibitorsIBA
10/2012
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
10/2012
1NociceptinIBA
03/2012
1Peptides (Polypeptides)IBA
03/2012
1Opioid Receptors (Opioid Receptor)IBA
03/2012
1GadoliniumIBA
09/2011
1protoporphyrin IXIBA
08/2010
1Adenosine Triphosphate (ATP)IBA
06/2010
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
06/2010
1PK 11195 (PK11195)IBA
02/2010
1PyridinesIBA
01/2008
1TritiumIBA
01/2008
1iomazenilIBA
07/2004
16- iodo- 2- (4'- N- (2- fluoroethyl)methylamino)phenylimidazo(1,2- a)pyridineIBA
04/2004
1gamma-Aminobutyric Acid (GABA)IBA
01/2004
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2002
1A 85380IBA
01/2001

Therapy/Procedure

1Therapeutics
08/2015